세미나

Enhancing Transplantable Biomaterials: The Role of Laser Processing in Human Synchronization

Abstract
Lasers, known for their monochromaticity, directionality, coherence, and focusability, have been utilized in healthcare and defense industries for over five decades. In recent years,
the use of lasers in medical and biomedical devices has significantly expanded. Given that such devices are attached to the skin or implanted into the human body,
it is critical to consider immune responses, inflammation control, cell adhesion and migration, and overall biocompatibility.
In this presentation, I will introduce laser-based strategies developed to enhance the biocompatibility and functionality of implantable medical devices.
First, I will present cases where laser-induced micro- and nano-scale surface patterning was used to control cell adhesion and migration.
These techniques have been applied in the development of intraocular lenses that prevent posterior capsule opacification and vascular stents designed to inhibit restenosis.
Next, I will introduce a laser-based coating technology for bioactive materials and share a successful case of its commercialization in dental implants.
Finally, I will discuss how the immune response affects implantable bioelectronic devices and introduce a laser fabrication approach that can suppress immune activation at the tissue-device interface.